HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → Phosphinic acid, dimethyl-, p-nitrophenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Dimethylphosphinic chloride | HCID 517954 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Phosphinic acid, dimethyl-, p-nitrophenyl ester | HCID 166793 | 26% |
Reaction Steps
The dimethylphosphinic acid 4-nitrophenyl ester reactant is prepared according to procedure E using 500 mg of dimethylphosphinic chloride, 214 mg of sodium hydride (50% in oil), and 618 mg of p-nitrophenol in solution in 10 ml of tetrahydrofuran. 700 mg of expected product are collected. Yield=26%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491710B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-bc896965a70a4185a42754af6b0c7f3c |
| Source note | uspto-grants-2009_02 |