HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(B)Thiophene-2-Boronic Acid → HCID 57562430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(B)Thiophene-2-Boronic Acid | HCID 2359 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 86598868 | HCID 86598868 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57562430 | HCID 57562430 | 2.9% |
Reaction Steps
The title compound is prepared according to procedure L employing 30 mg of 3-iodo-5-(methoxyphenylphosphinoyloxy)indazole-1-carboxylic acid tert-butyl ester, 21.2 mg of benzo[b]thiophene-2-boronic acid, 2.23 mg of 1,1′-bis(diphenylphosphino)ferrocene palladium(II) dichloride and 71 mg of cesium carbonate in 500 μl of dimethylformamide. 0.7 mg of phenylphosphonic acid 3-benzo[b]thiophen-2-yl-1H-indazol-5-yl ester methyl ester is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491710B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-8165cfd438f54af1a08f37cbbc6125a9 |
| Source note | uspto-grants-2009_02 |