HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromoaniline → Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromoaniline | HCID 7807 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate | HCID 11210451 | 256.6% |
Reaction Steps
Using general procedure A, 4-bromoaniline (1.23 g, 7.13 mmol) and 1-Boc-4-piperidone (1.42 g, 7.13 mmol) afforded 4-(4-bromo-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (6.5 g, 53%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-5ceac275ff5346239c9f78c152dac98d |
| Source note | uspto-grants-2009_02 |