Benzyl Bromide → HCID 68973625, compound

Participants

Reaction Steps

Using general procedure H with 4-(4-methoxycarbonyl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (see EXAMPLE 85) (1.0 g) and benzylbromide (0.54 mL, 4.50 mmol) and then using general procedure C afforded 4-(benzyl-piperidin-4-yl-amino)-benzoic acid methyl ester as a white solid (620 mg, 63% over 2 steps).

Provenance & Evidence