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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1726168Generated: November 4, 2026

tert-Butyl 4-oxopiperidine-1-carboxylate → HCID 68968593, compound

https://huagongshe.com/reaction/1726168

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantMethyl 4-(4-aminophenoxy)benzoateHCID 21907042—
ProductHCID 68968593HCID 6896859394%

Reaction Steps

Using general procedure A, 4-(4-aminophenoxy)-benzoic acid methyl ester (Fokin; et al., Chem. Abstr., 72, 12294, 1970) (556 mg, 2.29 mmol) and 1-Boc-4-piperidone (478 mg, 2.40 mmol) gave 4-[4-(4-methoxycarbonyl-phenoxy)-phenylamino]-piperidine-1-carboxylic acid tert-butyl ester (917 mg, 94%) as a crystalline solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491735B2
Source datasetuspto-grants-2009_02
ORD IDord-f01477878d0a4d2aa801a5a823f10f12
Source noteuspto-grants-2009_02