HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzonitrile → 1-Boc-4-[(4-cyanophenyl)amino]-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzonitrile | HCID 13396 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | 1-Boc-4-[(4-cyanophenyl)amino]-piperidine | HCID 18539207 | 52% |
Reaction Steps
Using general procedure A, 4-aminobenzonitrile (1.19 g, 10.1 mmol) and 1-Boc-4-piperidone (2.05 g, 10.3 mmol) gave 4-(4-cyano-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester as a white solid (1.58 g, 52%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-21d6ef92f42c496ba38ef21c51d55fb8 |
| Source note | uspto-grants-2009_02 |