HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate | HCID 1491503 | 78% |
Reaction Steps
Using general procedure A, 4-chloroaniline (640 mg, 5.0 mmol) and 1-Boc-4-piperidone (1.0 g, 5.0 mmol) afforded 4-(4-chloro-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.21 g, 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-c107dd12f3c84a20941cd163c0eeb64d |
| Source note | uspto-grants-2009_02 |