HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11461534, compound → tert-Butyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11461534 | HCID 11461534 | — |
| Reactant | HCID 178418287 | HCID 178418287 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | tert-Butyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate | HCID 10519988 | 99% |
Reaction Steps
A mixture of the above alcohol (450 mg, 1.38 mmol), SiO2 (1.50 g) and PCC (895 mg, 4.15 mmol) in CH2Cl2 (25 mL) was stirred at room temperature for 1 hour to afford 4-(4-chloro-benzoyl)-piperidine-1-carboxylic acid tert-butyl ester as a yellow solid (440 mg, 99%) after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-bd8f811ecef1479d9b45446c8ffbeae8 |
| Source note | uspto-grants-2009_02 |