2-(3-Oxobutyl)isoindoline-1,3-dione → HCID 68971528, compound

Participants

Reaction Steps

Using general procedure B with the above amine (221 mg, 0.70 mmol) and 2-(3-oxo-butyl)-isoindole-1,3-dione (305 mg, 1.40 mmol) and then using general procedure D afforded 3-{4-[2-(4-chloro-phenyl)-benzo[1,3]dioxol-2-yl]-piperidin-1-yl}-butylamine as a colourless oil (185 mg, 68% over 2 steps).

Provenance & Evidence