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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1726268Generated: November 3, 2026

2-(3-Oxobutyl)isoindoline-1,3-dione → HCID 68971734, compound

https://huagongshe.com/reaction/1726268

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Oxobutyl)isoindoline-1,3-dioneHCID 290728—
ReactantHCID 68972901HCID 68972901—
ProductHCID 68971734HCID 68971734—

Reaction Steps

Using general procedure B with the above amine (335 mg, 1.02 mmol) and 2-(3-oxo-butyl)-isoindole-1,3-dione (837 mg, 2.56 mmol) and then using general procedure D afforded 3-{4-[2-(4-methoxy-phenyl)-benzo[1,3]dioxol-2-yl]-piperidin-1-yl}-butylamine as a colourless oil (240 mg, 62% over 2 steps).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491735B2
Source datasetuspto-grants-2009_02
ORD IDord-f8cde069c0534ca8bbba217009d7bf8a
Source noteuspto-grants-2009_02