HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-aminobenzoate → HCID 68973000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-aminobenzoate | HCID 12082 | — |
| Reactant | (betaR)-beta-Methyl-4-oxo-1-piperidinepropanenitrile | HCID 68972438 | — |
| Product | HCID 68973000 | HCID 68973000 | — |
Reaction Steps
Using general procedure A with methyl 4-aminobenzoate (507 mg, 3.35 mmol) and (R)-3-(4-oxo-piperidin-1-yl)-butyronitrile (669 mg, 4.03 mmol) followed by general procedure J afforded 4-[1-((R)-3-amino-1-methyl-propyl)-piperidin-4-ylamino]-benzoic acid methyl ester as a white foam (390 mg, 38% over 2 steps).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-a6669403cec94685b3aa88208c75011d |
| Source note | uspto-grants-2009_02 |