HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → Tert-butyl 4-[(pyridin-3-yl)amino]piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | Tert-butyl 4-[(pyridin-3-yl)amino]piperidine-1-carboxylate | HCID 22499486 | 1,135.7% |
Reaction Steps
Using general procedure A, 3-aminopyridine (1.43 g, 1.01 mmol) and 1-Boc-4-piperidone (3.0 g, 1.0 mmol) afforded 4-(pyridin-3-ylamino)-piperidine-1-carboxylic acid tert-butyl ester as a white solid (3.15 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-849614a11b37430284ee080817b85a1d |
| Source note | uspto-grants-2009_02 |