HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-methoxy-3-Thiophenemethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Borane;tetrahydrofuran | HCID 2723981 | — |
| Reactant | 4-Methylthiophene-3-carboxylic acid | HCID 12993673 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-methoxy-3-Thiophenemethanol | HCID 15447735 | 100% |
Reaction Steps
4-Methylthiophene-3-carboxylic acid (158 mg, 1.00 mmol) was reduced with BH3-THF (1.0M in THF, 3.0 mL, 3.0 mmol) in THF (2 mL) at room temperature and treated with MeOH to give (4-methoxy-thiophen-3-yl)-methanol as an oil (144 mg, 100%) after work-up.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491735B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-3038ccec5c854034b0090a446af250a2 |
| Source note | uspto-grants-2009_02 |