Dicyclohexylcarbodiimide → HCID 68875593, compound

Participants

Reaction Steps

To the mixture of N-(tert-Butoxycarbonyl)-L-leucine (1.03 g, 4.46 mmol) and N-Hydroxysuccinimide (0.74 g, 6.43 mmol) in acetonitrile (30 ml) was added 1,3-Dicyclohexylcarbodiimide (1.24 g, 6.01 mmol) and stirred for 4 hr, at room temperature. The resulting precipitate was filtered off and the acetonitrile filtrate containing 2 was carried on to the next step. MS, m/z (relative intensity): 327 [M+1H, 100%], 327 [M+1H —C(CH3)3, 100%].

Provenance & Evidence