HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine → HCID 57563887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 3-Methoxyphenethylamine | HCID 74866 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 57563887 | HCID 57563887 | — |
Reaction Steps
1-Morpholin-4-ylmethyl-1,2,3,4-tetrahydro-isoquinoline was synthesized by a similar fashion as shown in Example 3-76a, except that in Step 1, phenethylamine was used to replace 2-(3-methoxy-phenyl)-ethylamine, and that in the first part of Step 3, morpholin was used to replace sodium methoxide as the nucleophile. The crude product was used directly in the next coupling step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07491794B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-4214cbd8bc004972b466e69b63ab20fb |
| Source note | uspto-grants-2009_02 |