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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1726431Generated: November 1, 2026

Phenethylamine → HCID 57563887, compound

https://huagongshe.com/reaction/1726431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
ReactantMorpholineHCID 8083—
Reactant3-MethoxyphenethylamineHCID 74866—
ReactantSodium MethoxideHCID 10942334—
ProductHCID 57563887HCID 57563887—

Reaction Steps

1-Morpholin-4-ylmethyl-1,2,3,4-tetrahydro-isoquinoline was synthesized by a similar fashion as shown in Example 3-76a, except that in Step 1, phenethylamine was used to replace 2-(3-methoxy-phenyl)-ethylamine, and that in the first part of Step 3, morpholin was used to replace sodium methoxide as the nucleophile. The crude product was used directly in the next coupling step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07491794B2
Source datasetuspto-grants-2009_02
ORD IDord-4214cbd8bc004972b466e69b63ab20fb
Source noteuspto-grants-2009_02