4-methylpiperazine-1-sulfonyl Chloride → 5-[2-Ethoxy-5-(4-methyl-1-piperazinyl) sulphonamidophenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

HRID 172681Notes

Reaction equation

HRID 172681 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([S:8](=[O:9])(=[O:10])[Cl:11])[CH2:6][CH2:7]1.[NH2:12][c:13]1[cH:14][cH:15][c:16]([O:33][CH2:34][CH3:35])[c:17](-[c:19]2[nH:20][c:21](=[O:32])[c:22]3[c:23]([n:24]2)[c:25]([CH2:29][CH2:30][CH3:31])[n:26][n:27]3[CH3:28])[cH:18]1>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([S:8](=[O:9])(=[O:10])[NH:12][c:13]2[cH:14][cH:15][c:16]([O:33][CH2:34][CH3:35])[c:17](-[c:19]3[nH:20][c:21](=[O:32])[c:22]4[c:23]([n:24]3)[c:25]([CH2:29][CH2:30][CH3:31])[n:26][n:27]4[CH3:28])[cH:18]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 111716174-methylpiperazine-1-sulfonyl ChlorideHCID 1357385605-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Product 1

HCID 1357109855-[2-Ethoxy-5-(4-methyl-1-piperazinyl) sulphonamidophenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Sources & evidence

ORD record
ord-ccdfbd8afd16450cbabdc4f413a92f76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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