HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(4-Benzyloxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-acrylic Acid Ethyl Ester → 3-(4-Hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-propionic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(4-Benzyloxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-acrylic Acid Ethyl Ester | HCID 69035743 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(4-Hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-propionic Acid Ethyl Ester | HCID 58566475 | — |
Reaction Steps
1.15 g (3.41 mmol) of the above prepared (E)-3-(4-benzyloxy-5,6,7,8-tetrahydro-naphthalen-1-yl)-acrylic acid ethyl ester was dissolved in 20 ml of tetrahydrofuran and hydrogenated over 0.3 g of 10% of palladium on charcoal as catalyst at ambient temperature and atmospheric pressure. Filtering off the catalyst and evaporating the solvent yielded 0.84 g of the title compound as grey solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07495001B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-2d872f6d990741db974a8eab93086a14 |
| Source note | uspto-grants-2009_02 |