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HRID 1727002作成日:2026年10月25日

(4-Benzyloxy-naphthalen-1-yloxy)-acetic Acid Ethyl Ester → (4-Hydroxy-naphthalen-1-yloxy)-acetic acid ethyl ester

https://huagongshe.com/reaction/1727002

反応式

関与物質

役割名称HCID仕込み量
反応物(4-Benzyloxy-naphthalen-1-yloxy)-acetic Acid Ethyl EsterHCID 69035941—
触媒PalladiumHCID 23938—
溶媒TetrahydrofuranHCID 8028—
生成物(4-Hydroxy-naphthalen-1-yloxy)-acetic acid ethyl esterHCID 6903758873.6%

反応手順

2.23 g (6.62 mmol) of (4-benzyloxy-naphthalen-1-yloxy)-acetic acid ethyl ester was dissolved in 20 ml of tetrahydrofuran and hydrogenated over 0.5 g of 10% of palladium on charcoal as catalyst at ambient temperature and atmospheric pressure. Filtering off the catalyst and evaporating the solvent yielded 1.2 g of the title compound as light brown solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07495001B2
出典データセットuspto-grants-2009_02
ORD IDord-c012bd1cc1394387a1f392d36b6dc0eb
出典メモuspto-grants-2009_02