反应详情

温度

160 °C

A mixture of dimethyl-4-nitroindane-2,2-dicarboxylate (4.84 g, 0.0167 mol), lithium chloride (0.84 g, 0.0198 mol), 1.1 mL water, and 18 mL dimethylsulfoxide was heated to 160° C. under nitrogen for two hours. It was then allowed to cool and the dimethylsulfoxide was removed under high vacuum. The residue was purified on silica (10%-100% CH2Cl2 in hexanes) to give 2.5 g white solid (65%).

1. temperatureto cool
2. customthe dimethylsulfoxide was removed under high vacuum
3. customThe residue was purified on silica (10%-100% CH2Cl2 in hexanes)