HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-nitro-2,3-dihydro-1H-indene-2-carboxylate → Methyl 4-amino-2,3-dihydro-1H-indene-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-nitro-2,3-dihydro-1H-indene-2-carboxylate | HCID 53415165 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 4-amino-2,3-dihydro-1H-indene-2-carboxylate | HCID 53350286 | 100% |
Reaction Steps
A mixture of methyl-4-nitroindane-2-carboxylate (2.4 g, 0.11 mol) and 10% palladium on carbon (1.1 g, 0.01 mol) in ethyl acetate (15 mL) was shaken under 55 PSI hydrogen for 1 hour. It was then filtered and the filtrate was concentrated to give 2.07 g white solid (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07494999B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-c3e1bf35b7dd49969c789402cbf29f3a |
| Source note | uspto-grants-2009_02 |