HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[4-(3-Benzyloxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide → 3-[4-(3-Hydroxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[4-(3-Benzyloxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide | HCID 57567116 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[4-(3-Hydroxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide | HCID 68828378 | 86.9% |
Reaction Steps
To a solution of 3-[4-(3-benzyloxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide (1.2 g) in 50 mL EtOH was added 10% Pd/C (100 mg). The resulting mixture was stirred under H2 for 4 h, filtered, and concentrated under reduced pressure to give 0.8 g of crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07495016B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-0976ff6980f54565b1123cfec164a133 |
| Source note | uspto-grants-2009_02 |