HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionic Acid → 3-Fluoro-2,6-dipropyl-4-propionylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionic Acid | HCID 1032 | — |
| Reactant | Trifluoromethanesulfonic acid | HCID 62406 | — |
| Reactant | 3-Fluoro-2,4-dipropylphenol | HCID 21985957 | — |
| Product | 3-Fluoro-2,6-dipropyl-4-propionylphenol | HCID 21985943 | — |
Reaction Steps
Propionic acid (9.07 g, 123 mmol) and 3-fluoro-2,4-dipropylphenol (9.60 g, 49.0 mmol) were mixed in trifluoromethanesulfonic acid (50 mL) as in Example 13, step 1. Purification by chromatography on silica gel using ethyl acetate:hexane (10:90) gave the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07495020B2 |
| Source dataset | uspto-grants-2009_02 |
| ORD ID | ord-9a21cde1adad476cb42593cfa6821560 |
| Source note | uspto-grants-2009_02 |