Ethyl isocyanate → HCID 24816055, compound

HRID 1727720Notes

Reaction equation

HRID 1727720 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[NH:19][C:20]([C:22]5[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH3:31])[CH3:30])=[CH:24][CH:23]=5)=[CH:21][C:14]=34)=[CH:11][N:10]([CH2:32][CH3:33])[N:9]=2)=[CH:4][CH:3]=1.[CH2:34]([N:36]=[C:37]=[O:38])[CH3:35]>>[CH3:35][CH2:34][NH:36][C:37]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[C:14]=3[CH:21]=[C:20]([C:22]3[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH3:30])[CH3:31])=[CH:24][CH:23]=3)[NH:19]4)=[CH:11][N:10]([CH2:32][CH3:33])[N:9]=2)=[CH:6][CH:7]=1)=[O:38]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 689980284-[3-(4-Aminophenyl)-1-ethyl-1h-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridine

Product 1

HCID 24816055HCID 24816055, compound

Procedure

Following the procedure described in Example 48 using 4-[3-(4-aminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine and ethyl isocyanate provided the title compound. ESMS (M+H)+: 508.4

Sources & evidence

ORD record
ord-f0a5d4f14d954990b4ee7503548bbb90
Source dataset
uspto-grants-2009_02
Patent number
US07495102B2

Reaction notes

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