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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1727735Generated: November 1, 2026

Trifluoroacetic acid → HCID 24816291, compound

https://huagongshe.com/reaction/1727735

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant1,1-dimethylethyl {2-[3-(4-{[(dimethylamino)carbonyl]amino}phenyl)-4-(2-{3-[(dimethylamino)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-1-yl]ethyl}methylcarbamateHCID 69458763—
SolventDichloromethaneHCID 6344—
ProductHCID 24816291HCID 24816291—

Reaction Steps

To 1,1-dimethylethyl {2-[3-(4-{[(dimethylamino)carbonyl]amino}phenyl)-4-(2-{3-[(dimethylamino)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-1-yl]ethyl}methylcarbamate (1.05 g, 1.65 mmol) was added 25% TFA in CH2Cl2 (25 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07495102B2
Source datasetuspto-grants-2009_02
ORD IDord-8a1931dd195f405aa9407f464ca98b58
Source noteuspto-grants-2009_02