Triethylamine → HCID 23022753, compound

Participants

Reaction Steps

[4-(6,7-Dimethoxy-4-quinolyloxy)phenyl]methylamine (100 mg) was dissolved in chloroform (10 ml) to prepare a solution. Triethylamine (0.3 ml), 4-tert-butylphenylboranic acid (100 mg), and copper(II) acetate (50 mg) were then added to the solution, and the mixture was stirred at room temperature for 3 days. The insolubles were removed by filtration, and the solvent was then removed by evaporation under the reduced pressure. The residue was purified by thin-layer chromatography on silica gel using chloroform/acetone for development to give the title compound (21 mg, yield 15%).

Provenance & Evidence