Triethylamine → HCID 44382259, compound

Participants

Reaction Steps

4-(6,7-Dimethoxy-4-quinolyloxy)phenol (starting compound 8) (24 mg) was dissolved in chloroform (2 ml) to prepare a solution. Triethylamine (0.3 ml), 4-tert-butylphenylboranic acid (50 mg), and copper(II) acetate (90 mg) were added to the solution, and the mixture was stirred at room temperature for 4 days. The insolubles were removed by filtration, and the solvent was then removed by evaporation under the reduced pressure. The residue was purified by thin-layer chromatography on silica gel using chloroform/acetone for development to give the title compound (20 mg, yield 58%).

Provenance & Evidence