1-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole → 9-{4-[4-(1-methyl-1H-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamide

HRID 172814Notes

Reaction equation

HRID 172814 reaction equation
[CH3:30][n:31]1[c:32]([N:40]2[CH2:41][CH2:42][NH:43][CH2:44][CH2:45]2)[n:33][c:34]2[c:35]1[cH:36][cH:37][cH:38][cH:39]2.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[C:10]2([CH2:23][CH2:24][CH2:25][CH2:26][Br:27])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3-[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:28][cH:29]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[C:10]2([CH2:23][CH2:24][CH2:25][CH2:26][N:43]3[CH2:42][CH2:41][N:40]([c:32]4[n:31]([CH3:30])[c:35]5[c:34]([n:33]4)[cH:39][cH:38][cH:37][cH:36]5)[CH2:45][CH2:44]3)[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3-[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:28][cH:29]1

Participants

3

Reactant 2

HCID 6675511-methyl-2-(piperazin-1-yl)-1H-benzo[d]imidazoleHCID 226362389-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide

Product 1

HCID 226362289-{4-[4-(1-methyl-1H-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamide

Sources & evidence

ORD record
ord-b194018a4047499098bf85da8b7bf6ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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