Potassium Carbonate → HCID 57565970, compound

Participants

Reaction Steps

5-Chloro-benzaldehyde (3.1 g, 20 mmol), 3-bromo-2,2-dimethyl-propan-1-ol (3 mL, 24 mmol), K2CO3 (5.5 g, 40 mmol) and KI (0.5 g) were mixed in DMF (20 mL). Then mixture was irradiated under microwave at 200° C. for 1 h. The mixture was filtered and the filtrate was concentrated. The residue was dissolved in ethyl acetate and washed with 1N NaOH. Then the organic layer was separated, dried over anhydrous Na2SO4 and concentrated to give title compound as yellow solid (Yield: 1.6 g).

Provenance & Evidence