HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172825Generated: October 27, 2026
Hydrochloric Acid → 1-[4-(4-Chloro-3-trifluoromethoxy-phenyl)-piperazin-1-yl]-2-[3-(1H-imidazol-2-yl)-pyrazolo[3,4-b]pyridin-1-yl]ethanone
https://huagongshe.com/reaction/172825
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Hexafluorophosphate | HCID 9886 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-benzotriazol-1-yl-tetramethyluronium | HCID 130500 | — |
| Reactant | 1-(4-Chloro-3-trifluoromethoxyphenyl)piperazine | HCID 59242686 | — |
| Reactant | 2-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid | HCID 136174646 | — |
| Product | 1-[4-(4-Chloro-3-trifluoromethoxy-phenyl)-piperazin-1-yl]-2-[3-(1H-imidazol-2-yl)-pyrazolo[3,4-b]pyridin-1-yl]ethanone | HCID 135882256 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
| ORD ID | ord-b559d0b4b0284b1b93a9c9a2337055f1 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
