HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → Methyl 3-(3,4-dichlorophenyl)prop-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(3,4-Dichlorophenyl)prop-2-enoic acid | HCID 14548 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Methyl 3-(3,4-dichlorophenyl)prop-2-enoate | HCID 54151376 | 57.9% |
Reaction Steps
3,4-Dichlorocinnamic acid (6.5g) (Ex.Aldrich), dimethylsulphate (3.77 g), potassium carbonate (4.13 g) and anhydrous acetone heated together under reflux. After cooling and filtration the acetone was removed and the residue recrystallised (80:20-hexane: ether) to give methyl 3,4-dichlorocinnamate as a colourless solid (4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05326755 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-5d3b7af13a60485583fb009e1414431f |
| Source note | uspto-grants-1994_07 |