Methanesulfonyl chloride → N-[1-phenyl-2-(4-methanesulfonylaminophenyl)ethyl]-alpha-phenyl-benzeneacetamide

HRID 1728358Notes

Reaction equation

HRID 1728358 reaction equation
[C:1]1([CH:7]([NH:16][C:17](=[O:31])[CH:18]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:8][C:9]2[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:32][S:33](Cl)(=[O:35])=[O:34]>>[C:1]1([CH:7]([NH:16][C:17](=[O:31])[CH:18]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:8][C:9]2[CH:14]=[CH:13][C:12]([NH:15][S:33]([CH3:32])(=[O:35])=[O:34])=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 9953161N-[2-(4-Amino-phenyl)-1-phenyl-ethyl]-2,2-diphenyl-acetamide

Product 1

HCID 10028310N-[1-phenyl-2-(4-methanesulfonylaminophenyl)ethyl]-alpha-phenyl-benzeneacetamide

Procedure

Treat the product of Example 3 with methanesulfonylchloride to obtain N-[1-phenyl-2-(4-methanesulfonylaminophenyl)ethyl]-α-phenyl-benzeneacetamide, m.p. 200°-202° C.

Sources & evidence

ORD record
ord-f4ce776765a4419f990b250654843302
Source dataset
uspto-grants-1994_07
Patent number
US05326762

Reaction notes

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