Nitric Acid → HCID 178526881, compound

HRID 1728401Notes

Reaction equation

HRID 1728401 reaction equation
[C:1]1([C:7]2[N:12]=[C:11]([OH:13])[CH:10]=[C:9]([OH:14])[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:15]([O-])([OH:17])=[O:16]>C(O)(=O)C.O>[C:1]1([C:7]2[N:12]=[C:11]([OH:13])[C:10]([N+:15]([O-:17])=[O:16])=[C:9]([OH:14])[N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 2

HCID 944Nitric AcidHCID 178516639HCID 178516639, compound

Product 1

HCID 178526881HCID 178526881, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

To a suspension of 2-Phenyl-4,6-dihydroxypyrimidine (12 g) in 35 mL of acetic acid is added 12 mL of 90% nitric acid and the mixture is heated at 50° C. for 45 min. The reaction mixture is diluted with 150 mL of water and the product is collected, washed with water and ethanol and oven dried to afford 2-Phenyl-5-nitro-4,6-dihydroxypyrimidine as a pink solid.

Workup

  1. customthe product is collected
  2. washwashed with water and ethanol and oven
  3. customdried

Sources & evidence

ORD record
ord-3564a3a6e7804ca1ab808d48cebd0ac6
Source dataset
uspto-grants-1994_07
Patent number
US05326868

Reaction notes

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