HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → L-Asparagine, monohydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | L-Aspartic Acid | HCID 5960 | — |
| Reactant | (-)-Asparagine | HCID 6267 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | L-Asparagine, monohydrate | HCID 170358 | — |
Reaction Steps
A method for the preparation of asparagine, comprising the methylation of aspartic acid in the presence of methanol and sulfuric acid to yield beta-methyl aspartic sulfate, subsequently aminating the intermediate in-situ by the addition of aqueous ammonia and heat to form asparagine monohydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05326908 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-3cbf46ed1d1549f89e21c0b350b2ef82 |
| Source note | uspto-grants-1994_07 |