N-bromobutanimide → HCID 19018248, compound

Participants

Reaction Steps

A solution of 1.3 g (5.2 mmol) of 4-(4-methylphenoxy)carboxyglutarimide, 1.0 g (5.7 mmol) of N-bromosuccinimide and 0.02 g of benzoyl peroxide in 30 ml of carbon tetrachloride was refluxed for 16 hours, cooled to room temperature, evaporated and the residue dissolved in 200 ml of ethyl acetate. The EtOAc layer was washed with water, dried over Na2SO4 and evaporated to give 1.6 g of the crude product.

Provenance & Evidence