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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1728489Generated: October 31, 2026

Hydrochloric Acid → HCID 178473981, compound

https://huagongshe.com/reaction/1728489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178473979HCID 178473979—
CatalystPalladiumHCID 23938—
SolventEthylacetate methanolHCID 21584119—
ProductHCID 178473981HCID 17847398133%

Reaction Steps

A methanol/ethyl acetate (3 mL/0.5 mL) solution of compound 29 (200 mg, 0.38 mmol) and 1N HCl (0.5 mL), containing 10% palladium on carbon, was stirred under a hydrogen atmosphere until TLC indicated the disappearance of the starting material (15 min). The suspension was filtered through a pad of Celite, and the filtrate was concentrated to afford 37 mg (33%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05326863
Source datasetuspto-grants-1994_07
ORD IDord-b5c5b13246394cdbbb255fb6ff7d8f3f
Source noteuspto-grants-1994_07