Ethyl chloroformate → HCID 54066800, compound

HRID 1728504Notes

Reaction equation

HRID 1728504 reaction equation
[C:1]([C:3](=[CH:14][C:15]1[CH:20]=[C:19]([OH:21])[C:18]([OH:22])=[C:17]([OH:23])[CH:16]=1)[C:4]([O:6][CH2:7][CH2:8][C:9]1[S:10][CH:11]=[CH:12][CH:13]=1)=[O:5])#[N:2].C(C(=CC1C=CC(O)=C(O)C=1)[C:27]([O:29][C:30]1[CH:35]=CC=CC=1)=[O:28])#N.Cl[C:46]([O:48][CH2:49][CH3:50])=[O:47]>>[C:1]([C:3](=[CH:14][C:15]1[CH:16]=[C:17]([O:23][C:46]([O:48][CH2:49][CH3:50])=[O:47])[C:18]([O:22][C:4]([O:6][CH2:7][CH3:8])=[O:5])=[C:19]([O:21][C:27]([O:29][CH2:30][CH3:35])=[O:28])[CH:20]=1)[C:4]([O:6][CH2:7][CH2:8][C:9]1[S:10][CH:11]=[CH:12][CH:13]=1)=[O:5])#[N:2]

Participants

4

Reactant 3

HCID 10928Ethyl chloroformateHCID 53663840HCID 53663840, compoundHCID 53836576HCID 53836576, compound

Product 1

HCID 54066800HCID 54066800, compound

Procedure

By using 2-(2-thienyl)-ethyl 2-cyano-3-(3,4,5-trihydroxyphenyl)-2-propenoate in lieu of phenyl 2-cyano-3-(3,4-dihydroxyphenyl)-2-propenoate and changing the amount of ethyl chloroformate to 3.3 equivalents in the process of Example 1, the title compound was obtained.

Sources & evidence

ORD record
ord-a6a856a5abb44bfc9cf6f91501c69977
Source dataset
uspto-grants-1994_07
Patent number
US05326785

Reaction notes

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