(R)-(+)-1,1,1-Trifluoro-2-octanol → (R)-1,1,1-Trifluorodecan-2-ol

HRID 1728524Notes

Reaction equation

HRID 1728524 reaction equation
[CH2:1](OC(C1C=CC(C2C=CC(O)=CC=2)=CC=1)=O)[CH2:2]CCCCCCCC.[F:27][C:28]([F:38])([F:37])[C@H:29]([OH:36])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].C(C1C=CC(C2C=CC(O)=CC=2)=CC=1)CCCCCCCCC>>[F:27][C:28]([F:37])([F:38])[C@H:29]([OH:36])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:1][CH3:2]

Participants

4

Reactant 3

HCID 2779099(R)-(+)-1,1,1-Trifluoro-2-octanolHCID 148475754-Decyloxycarbonyl-4'-hydroxybiphenylHCID 150849074-(4-Decylphenyl)phenol

Product 1

HCID 2779103(R)-1,1,1-Trifluorodecan-2-ol

Procedure

Example 22 was repeated except that 4-decyloxycarbonyl-4'-hydroxybiphenyl and (R)-(+)-1,1,1-trifluoro-2-octanol were used in place of the 4-decyl-4'-hydroxybiphenyl and the (R)-(+)-1,1,1-trifluoro-2-decanol, respectively, to obtain the titled compound.

Sources & evidence

ORD record
ord-8992a3ef4eaf48d8b621dee793c05af7
Source dataset
uspto-grants-1994_07
Patent number
US05328641

Reaction notes

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