3-Isocyanatopyridine → HCID 19016517, compound

HRID 1728606Notes

Reaction equation

HRID 1728606 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([NH:11][CH3:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([N:19]=[C:20]=[O:21])[CH:14]=1>>[CH3:12][N:11]([C:7]1[CH:6]=[C:5]2[C:10](=[CH:9][CH:8]=1)[N:2]([CH3:1])[CH:3]=[CH:4]2)[C:20]([NH:19][C:15]1[CH:14]=[N:13][CH:18]=[CH:17][CH:16]=1)=[O:21]

Participants

3

Reactant 2

HCID 27604933-IsocyanatopyridineHCID 13865738HCID 13865738, compound

Product 1

HCID 19016517HCID 19016517, compoundYield 45%

Procedure

The title compound was prepared from 1-methyl-5-methylamino-1H-indole (D15) and 3-pyridyl isocyanate (D4) using a procedure similar to that described for Example 2 Method B. The crude produce was obtained in 45% yield.

Workup

  1. customThe crude produce
  2. customwas obtained in 45% yield

Sources & evidence

ORD record
ord-927f39fe00b54b079a0148b67adc487d
Source dataset
uspto-grants-1994_07
Patent number
US05328922

Reaction notes

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