Phosgene → HCID 19016482, compound

HRID 1728609Notes

Reaction equation

HRID 1728609 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH3:11])[C:6]([CH3:12])=[C:5]2[CH2:13][CH3:14].[C:15](Cl)(Cl)=[O:16].[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1>>[CH3:11][N:7]1[C:8]2[C:4](=[CH:3][C:2]([NH:1][C:15]([NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)=[O:16])=[CH:10][CH:9]=2)[C:5]([CH2:13][CH3:14])=[C:6]1[CH3:12]

Participants

4

Reactant 3

HCID 6371PhosgeneHCID 104392-AminopyridineHCID 19016521HCID 19016521, compound

Product 1

HCID 19016482HCID 19016482, compound

Procedure

The title compound was prepared from the aminoindole (D1), phosgene and 2-aminopyridine using a procedure similar to that described for Example 1, the product being isolated as the free base, m.p. 120°-123° C.

Workup

  1. customthe product being isolated as the free base, m.p. 120°-123° C.

Sources & evidence

ORD record
ord-85eeaf50020e4d29a54f555d8b04bfd2
Source dataset
uspto-grants-1994_07
Patent number
US05328922

Reaction notes

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