HCID 131718545, compound → HCID 131718551, compound

HRID 1728660Notes

Reaction equation

HRID 1728660 reaction equation
[ClH:1].[CH2:2]([N:4]([CH2:34][CH3:35])[C:5]1[CH:10]=[CH:9][C:8]([C@@H:11]2[CH2:16][CH2:15][N:14](CC(C)CC)[CH2:13][C@H:12]2[CH2:22][O:23][C:24]2[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=2)=[CH:7][CH:6]=1)[CH3:3].Cl.CN(C)C1C=CC([C@@H]2CCNC[C@H]2COC2C=CC(C(F)(F)F)=CC=2)=CC=1>>[ClH:1].[CH2:34]([N:4]([CH2:2][CH3:3])[C:5]1[CH:10]=[CH:9][C:8]([C@@H:11]2[CH2:16][CH2:15][NH:14][CH2:13][C@H:12]2[CH2:22][O:23][C:24]2[CH:25]=[CH:26][C:27]([C:30]([F:33])([F:31])[F:32])=[CH:28][CH:29]=2)=[CH:7][CH:6]=1)[CH3:35]

Participants

3

Reactant 2

HCID 131718545HCID 131718545, compoundHCID 131718552HCID 131718552, compound

Product 1

HCID 131718551HCID 131718551, compoundYield 23%

Procedure

Preparation by dealkylation of (44) as described for compound (41). Yield 23%. M.p. 220.5°-227.6° C.

Sources & evidence

ORD record
ord-9809f8f7d6fe419fb8eb0bff7c837664
Source dataset
uspto-grants-1994_07
Patent number
US05328917

Reaction notes

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