HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → Methyl 4-(tetradecyloxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | Methyl 4-(tetradecyloxy)benzoate | HCID 3312490 | — |
Reaction Steps
A mixture of 150 g methyl-4-hydroxybenzoate, 1.5 L 2-butanone, 272.5 g potassium carbonate and 293 ml 1-bromotetradecane is heated at reflux for 66 hours. The reaction is cooled to room temperature, filtered, the filtrate concentrated in vacuo and the residue recrystallized from methylene chloride/hexane to give 258.8 g of the desired product. MP 56°-58° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328921 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-80879f59418e43f39a9367b8bcccbe3f |
| Source note | uspto-grants-1994_07 |