HuagongsheHuagongshe Chemistry Print Report · For research reference only
Myristyl bromide → 3-(1,1-Dimethylethyl)-4-(tetradecyloxy)benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 3-tert-butyl-4-hydroxybenzoate | HCID 13207060 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-(1,1-Dimethylethyl)-4-(tetradecyloxy)benzoic acid methyl ester | HCID 53858411 | — |
Reaction Steps
A mixture of 30.0 g 3-(1,1-dimethylethyl)-4-hydroxybenzoic acid methyl ester, 42.9 ml of 1-bromotetradecane, 47.8 g of potassium carbonate and 700 ml of acetone is refluxed for 48 hours. The cooled reaction is filtered, concentrated in vacuo and purified by column chromatography (silica ge1:0-3% ethyl acetate/hexane) to give 38.8 g of the desired product as colorless prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328921 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-09c2ee71089d42ebad72648df48969d2 |
| Source note | uspto-grants-1994_07 |