HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → N-Acetyl-4-methoxy-3-(tetradecyloxy)-N-(2-pyridinylmethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(pyridin-2-ylmethyl)acetamide | HCID 5084090 | — |
| Reactant | HCID 19016259 | HCID 19016259 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-Acetyl-4-methoxy-3-(tetradecyloxy)-N-(2-pyridinylmethyl)benzamide | HCID 10255296 | 30.6% |
Reaction Steps
The title compound is prepared by the procedure of Example 27 using 1.19 g of product from Example 43, 0.490 g of product from Example 12, 0,157 g of washed 50% sodium hydride and 12 ml of tetrahydrofuran. The residue is purified by column chromatography (silica gel:35% ethyl acetate/hexane) to give 0.472 g of the desired product as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328921 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-5aff96cf2186459285db0d7ee4fc1676 |
| Source note | uspto-grants-1994_07 |