Sodium hydride → 4-Methyl-N-(2-pyridinylmethyl)-N-[[3-(tetradecyloxy)phenyl]methyl]benzenesulfonamide

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Reaction Steps

The title compound is prepared by the procedure of Example 27, using 1.23 g of product from Example 79, 1.71 g of product from Example 25, 0.321 g of washed 50% sodium hydride and 70 ml of tetrahydrofuran. The reaction is stirred at room temperature for 68 hours. The residue is purified by column chromatography (silica gel: 25% ethyl acetate/hexane) to give 1.15 g of the desired product as a colorless oil, which crystallized on standing.

Provenance & Evidence