HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 4-Hexadecyloxyphenoxyacetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 4-(Hexadecyloxy)phenol | HCID 4377937 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Hexadecyloxyphenoxyacetic acid methyl ester | HCID 10250794 | 89.4% |
Reaction Steps
A mixture of 23 g of product from Example 84, 13.15 g of methyl bromoacetate, 10.45 g of potassium carbonate and 200 ml of acetone is heated at reflux for 24 hours. The reaction is cooled, chloroform added, filtered and concentrated. The residue is recrystallized from hexane to give 25 g of the desired product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328921 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-a965271ce21d4e12b6d1f6dcdcacd11a |
| Source note | uspto-grants-1994_07 |