Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Myristyl bromide | HCID 8208 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-Hydroxybenzamide | HCID 65052 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(Tetradecyloxy)benzamide | HCID 12361468 | 47.7% |
Reaction Steps
A mixture of 50 g of 4-hydroxybenzamide, 106.1 g of 1-bromotetradecane, 75.59 g of potassium hydroxide, 5.46 g of sodium iodide and 600 ml of dimethylformamide is heated at 110° C. for 24 hours; followed by stirring at room temperature for 72 hours. The reaction is poured into water, the resulting solid collected and washed with water. The solid is recrystallized first from chloroform then ethyl acetate to give 58 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05328921 |
|---|
| Source dataset | uspto-grants-1994_07 |
|---|
| ORD ID | ord-4a5173b08e0d48dfbdfa5b0ed3f19c8c |
|---|
| Source note | uspto-grants-1994_07 |
|---|
