HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-[[4-(Tetradecyloxy)phenyl]methyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(Tetradecyloxy)benzenemethanamine | HCID 11723498 | — |
| Reactant | Isonicotinoyl chloride hydrochloride | HCID 12262826 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[[4-(Tetradecyloxy)phenyl]methyl]benzamide | HCID 19015909 | 76.9% |
Reaction Steps
The title compound is prepared by the procedure of Example 116 using 3.0 g of product from Example 99, 2.01 g Of isonicotinoyl chloride hydrochloride, 3.8 g of triethylamine and 100 ml of methylene chloride. The product is purified by chromatography (silica gel: 3.5% methyl alcohol/chloroform) followed by recrystallization from heptane/methanol to give 3.06 g of the desired product as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05328921 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-94d89a48f68c434f9423d93158a5a283 |
| Source note | uspto-grants-1994_07 |