Sodium hydride → N-Acetyl-4-(decyloxy)-3-(1,1-dimethylethyl)-N-(3-pyridinylmethyl)benzamide

Participants

Reaction Steps

The title compound is prepared by the procedure of Example 27, using 0.90 g of product from Example 33, 0.316 g of washed 50% sodium hydride, 2.57 g of product from Example 14 and 25 ml of dry tetrahydrofuran. The residue is purified by chromatography (silica gel: 40% ethyl acetate/hexane) to give 1.81 g of the desired product as a yellow oil which crystallizes on standing.

Provenance & Evidence