Sodium hydride → N-Acetyl-3-(1,1-dimethylethyl)-4-(tetradecyloxy)-N-(4-pyridinylmethyl)benzamide

Participants

Reaction Steps

The title compound is prepared by the procedure of Example 27, using 0.90 g of product from Example 15, 0.316 g of washed 50% sodium hydride, 2.57 g of product from Example 33 and 25 ml of dry tetrahydrofuran. The residue is purified by chromatography (silica gel: 40% ethyl acetate/hexane) to give 0.275 g of desired product as a yellow oil which crystallizes on standing.

Provenance & Evidence