Pyridine → HCID 19014751, compound

Participants

Reaction Steps

To a mixture of 7.02 g of aniline and 4.48 g of pyridine in 200 ml of methylene chloride is added 20 g of product from Example 3. The reaction is stirred at room temperature for 2 hours; diluted with chloroform and water and heated to dissolve the solids. The layers are separated and the organic layer is washed with hot dilute hydrochloric acid. The organic layer is dried, concentrated in vacuo and the residue is recrystallized from chloroform/hexane to give 23.1 g of the desired product.

Provenance & Evidence